Bring the American Philanthropist
and the American Innovator Together
Turn charitable capital into long-term impact by funding breakthrough companies in climate, health, and life sciences.
Who We Are
NextRound and Human + Machine Rise Ventures collaborate to
direct patient philanthropic capital toward climate and health / life sciences.
DiDi Dione
Shapes how donor capital is deployed
Michael Porteous
Leads deeper follow-up conversations
John Pappas
Creates a comfortable first introduction
Charlie Hoppenstein
Creates a comfortable first introduction
Experience & network: 40+ vetted medtech, biotech, AI health, climate, and robotics companies in active pipeline.NextRound and Human + Machine Rise Ventures collaborate to direct patient philanthropic capital toward climate and health / life sciences.
The Big Idea / Why This Exists
A donor-friendly 30,000-foot narrative: philanthropy can help create tomorrow’s solution, not only fund today’s relief.
The Problem
Philanthropy today is designed for immediate relief:
- Treating patients today
- Addressing urgent, short-term needs
At the same time, the companies building long-term solutions remain underfunded.
The Solution
Use donor-advised fund money
to support breakthrough ventures in climate, health, life sciences and other mission-aligned innovation.
The Contrast
Write a check to charity:
- money may be spent next
Tuesday
Put the same money in a DAF
- it can help fund tomorrow’s
long-term solution to the same
problem and create a
purposeful legacy for the
donors and multiplier effect on
the amounts donated.
What’s Different About This Fund
This first deck should make the differentiation obvious in plain English.
1. Direct Attribution / Naming Rights
If a company succeeds, a donor can have naming rights attached to the breakthrough; for example a drug, program, or other visible legacy outcome.
2. Donor-Friendly Economics
2% annual fee, with no traditional carry charged to the donor. The startup side pays with options, so donors are not paying a standard 2 & 20 venture structure.
3. Designed for Ongoing Impact
The structure encourages annual commitments, so promising companies are not starved of follow-on capital at the most fragile stage.
How It Works for the Donor
A clean explanation used before a deeper conversation.
1. Donor Contributes to DAF
Gets an immediate tax receipt through the normal donor-advised fund process.
2. DAF Allocates
Option A: Diversified fund
Option B: Bespoke portfolio
(e.g., ovarian cancer only, neuro-degenerative diseases only)
3. Capital Goes into Curated Startups
Targets climate + health / life science innovation selected by the platform team.
4. Outcomes
Same tax receipt as usual.
Potential naming rights / legacy if a funded startup succeeds.
Simple talk track: “You follow a familiar charitable path, but your giving can now support a curated innovation portfolio or a bespoke mission area you care deeply about.”
Customization & Donor Legacy
Connect the donor’s philanthropy to what is closest to their heart.
Why This Is Attractive to Sophisticated Donors
Address what a family office or foundation professional will care about at a high level.
Risk
Profile
No additional financial risk versus normal philanthropy in the donor’s frame of reference; the tax receipt is locked in through the usual DAF process.
Governance / Professionalism
Deals are vetted and managed by an experienced GP with a deep pipeline and a venture-philanthropy operating lens.
Operational
Simplicity
Works through existing DAF/foundation structures instead of asking donors to learn a new charitable process.
Impact
Narrative
A donor or board can say: “We are funding the companies that could eliminate the problem, not just treat it.”
Most Philanthropy Funds the Present. Not the Solution.
Philanthropy today is designed for immediate relief:
- Treating patients today
- Addressing urgent, short-term needs
At the same time, the companies building long-term solutions remain underfunded.
- Atherosclerosis
- Experimental Transplantation
- Cancer Biology
History
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Why?
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Next Step:
Talk to Michael
If this resonates, the next step is a 30-minute conversation with Michael to:
- Map current philanthropic goals
- Explore whether a tailored impact portfolio makes sense
- Answer technical and structural questions about DAFs, fees,
naming rights, and how the platform works
Michael Porteous
Book an Intro Call